Open Access Open Access  Restricted Access Subscription or Fee Access

Does Parkinson's disease interfere with electromyographic fatigue of masticatory muscles?

M. Palinkas, L. Pagnano, G. P. da Siva, J. E.C. Hallak, N. S. da Silva, I. H. Regalo, E. D. Verri, S. C.H. Regalo, S. Siéssere


Parkinson’s disease is a neurodegenerative disease with manifestations related to oxidative stress and damage to the skeletal striated musculature. This study evaluated the electromyographic fatigue of the masseter and temporal muscles in individuals with Parkinson’s disease. The median frequency of the normotensive electromyographic signal was analyzed in 16 individuals, aged between 50 and 70 years, with Parkinson’s disease in stages I and III of the Hoehn and Yahr disability scale (n=8) or without the disease (n=8). The data were tabulated and analyzed statistically (t-test, p <.05). Compared with the group without Parkinson’s disease, the group with the disease showed an increase in the median frequency, with significant differences for the right masseter (p=.05) and the right temporal (p=.03) muscles. The results suggest that there is a link between Parkinson’s disease and functional alterations of the masticatory system, especially when electromyographic fatigue is assessed.


: Parkinson's disease; Fatigue; EMG; Medium Frequency; Masticatory Muscles

Full Text:



Burks S, Raymick J, Robinson B, Hanig J, Sarkar S. Neuroprotective effects of acetyl-l-carnitine (ALC) in a chronic MPTP-induced Parkinson's disease mouse model: Endothelial and microglial effects. Neurosci Lett.,703:86-95, 2019.

Kalia LV, Lang AE. Parkinson's disease. Lancet.,386:896-912,2015.

Lian TH, Guo P, Zuo LJ, Hu Y, Yu SY, Yu QJ, et al. Tremor-Dominant in Parkinson Disease: The Relevance to Iron Metabolism and Inflammation. Front Neurosci.,13:255,2019.

Fraiwan L, Khnouf R, Mashagbeh AR. Parkinson's disease hand tremor detection system for mobile application. J Med Eng Technol., 40:127-134,2016.

Tucker H, Mahoney E, Chhetri A, Unger K, Mamone G, Kim G, et al. Deep brain stimulation of the ventroanterior and ventrolateral thalamus improves motor function in a rat model of Parkinson's disease. Exp Neurol., 317:155-167, 2019.

Goiato MC. Duchenne muscular dystrophy and the stomatognathic system. Dev Med Child Neurol.,58:650,2016.

Oliveira LF, Palinkas M, Vasconcelos PB, Regalo IH, Cecilio FA, Oliveira EF, et al. Influence of age on the electromyographic fatigue threshold of the masseter and temporal muscles of healthy individuals. Arch Oral Biol., 84:1-5,2017.

Wanshi Arnoni V, Batista de Vasconcelos P, Sousa LG, Ferreira B, Palinkas M, Acioli Righetti M, et al. Evaluation of the electromyographic fatigue of the masseter and temporalis muscles in individuals with osteoporosis. Cranio., 37:254-263, 2019.

Politti F, Casellato C, Kalytczak MM, Garcia MB, Biasotto-Gonzalez DA. Characteristics of EMG frequency bands in temporomandibullar disorders patients. J Electromyogr Kinesiol., 31:119-125, 2016.

Huang YZ, Chang FY, Liu WC, Chuang YF, Chuang LL, Chang YJ. Fatigue and Muscle Strength Involving Walking Speed in Parkinson's Disease: Insights for Developing Rehabilitation Strategy for PD. Neural Plast.,2017:1941980,2017.

Szyszka-Sommerfeld L, Machoy M, Lipski M, Woźniak K. The Diagnostic Value of Electromyography in identifying patients with pain-related temporomandibular disorders. Front Neurol.,10:180, 2019.

Suo X, Lei D, Li N, Cheng L, Chen F, Wang M, et al. Functional Brain Connectome and Its Relation to Hoehn and Yahr Stage in Parkinson Disease. Radiology., 285:904-913, 2017.

Ikeda M, Kataoka H, Ueno S. Can levodopa prevent cognitive decline in patients with Parkinson's disease? Am J Neurodegener Dis., 2017;6:9-14,2017.

Abboud J, Lardon A, Boivin F, Dugas C, Descarreaux M. Effects of Muscle Fatigue, Creep, and Musculoskeletal Pain on Neuromuscular Responses to Unexpected Perturbation of the Trunk: A Systematic Review. Front Hum Neurosci.,10:667, 2017.

Hermens H. J. Commission Des Communautés E., Biomedical Health Research, P. SENIAM: European Recommendations for Surface Electromyography: Results of the SENIAM Project. Enschede: Roessingh Research and Development. 1999.

Di Palma E, Tepedino M, Chimenti C, Tartaglia GM, Sforza C. Effects of the functional orthopaedic therapy on masticatory muscles activity. J Clin Exp Dent., 9:e886-e891, 2017.

Gibelli D, Borlando A, Barni L, Sartori P, Cappella A, Pucciarelli V, et al. Anatomy of Infraorbital Foramen: Influence of Sex, Side, and Cranium Size. J Craniofac Surg., 30:1284-1288, 2019.

Schwartz C, Tubez F, Wang FC, Croisier JL, Brüls O, Denoël V, Forthomme B. Normalizing shoulder EMG: An optimal set of maximum isometric voluntary contraction tests considering reproducibility. J Electromyogr Kinesiol., 37:1-8, 2017.

Yakabi K, Yamaguchi N, Ono S, Yoshida N, Hosomi E, Hayashi K, et al. Open Label Trial of the Efficacy and Safety Profile of Rikkunshito used for the Treatment of Gastrointestinal Symptoms in Patients with Parkinson's Disease: A Pilot Study. Curr Ther Res Clin Exp.,87:1-8, 2017.

Huang HW, Ju MS, Lin CC. Flexor and extensor muscle tone evaluated using the quantitative pendulum test in stroke and parkinsonian patients. J Clin Neurosci., 27:48-52,2016.

Tezze C, Romanello V, Desbats MA, Fadini GP, Albiero M, Favaro G, et al. Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence. Cell Metab.,25:1374-1389.e6., 2017.

Arnaldi D, Latimier A, Leu-Semenescu S, De Carli F, Vidailhet M, Arnulf I. Does Postural Rigidity Decrease during REM Sleep without Atonia in Parkinson Disease? J Clin Sleep Med.,12:839-847, 2016.

Puspita L, Chung SY, Shim JW. Oxidative stress and cellular pathologies in Parkinson's disease. Mol Brain., 10:53, 2017.

Barichella M, Pinelli G, Iorio L, Cassani E, Valentino A, Pusani C, et al. Sarcopenia and Dynapenia in Patients With Parkinsonis. J Am Med Dir Assoc.,17:640-646,2016.

Peyron MA, Lassauzay C, Woda A. Effects of increased hardness on jaw movement and muscle activity during chewing of visco-elastic model foods. Exp Brain Res., 142:41-51, 2002.

Castroflorio T, Falla D, Tartaglia GM, Sforza C, Deregibus A. Myoelectric manifestations of jaw elevator muscle fatigue and recovery in healthy and TMD subjects. J Oral Rehabil., 39:648-658,2012.

Woźniak K, Lipski M, Lichota D, Szyszka-Sommerfeld L. Muscle fatigue in the temporal and masseter muscles in patients with temporomandibular dysfunction. Biomed Res Int., 2015:269734, 2015, 2015.



  • There are currently no refbacks.